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I'm a geek working as a distance learning specialist for a large corporation.

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Living in a house with 3 females has apparently done me in. I think I need to turn in my man card. Either that, or I have to stop watching moviesWhen did I become a girl?

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I'm not even exaggerating. This blows my mind. There are certainly cakes that are unbelievably beautiful (and this is not one of them), but the level of detail on thisThe best cake I've ever seen

“Justice League of America” Moves Forward - Slice of Scifi I'm sorry. I just can't picture this movie being made well any time in the next 5 years. As I said in“Justice League of America” Moves Forward - Slice of Scifi

The Simple Dollar » Everything You Ever Really Needed to Know About Personal Finance on the Back of Five Business Cards Lately I've felt like Trent was recycling the same advicePersonal Finance on 5 business cards

Pennsylvania Gas Prices - Find Cheap Gas Prices in Pennsylvania Now this is a useful site (assuming you live in PA, anyway). Not only can you find the lowest (and highest) gasPennsylvania Gas Prices - Find Cheap Gas Prices in Pennsylvania

Lee posted his "Nerd badge" score recently. He failed to get it, and rightly so. Not because of any lack of nerd-dom on his part, but because of the idiocyThe Nerd Badge is invalidly valid, therefore I get one

At a recent Rangers game, a couple was caught on film denying a game ball to a crying toddler, and they have been put through the social media ringer over"Stolen" baseballs

A cure for Type I diabetes?

Diabetes breakthrough

Before you get too excited, let me say this: from my read of the article, it’s a long time before humans could benefit, and even when they can, you’ll probably have to catch it within a certain amount of time.

In a discovery that has stunned even those behind it, scientists at a Toronto hospital say they have proof the body’s nervous system helps trigger diabetes, opening the door to a potential near-cure of the disease that affects millions of Canadians.

Diabetic mice became healthy virtually overnight after researchers injected a substance to counteract the effect of malfunctioning pain neurons in the pancreas.

The link to the nervous system is the breakthrough idea. Until this point, the auto-immune system was seen as the problem. But recently the researchers in the article tried a nerve inhibitor that actually removed the disease from infected mice.

In diabetes, the inflammation (and eventually death) of pancreatic islet cells, which produce the insulin we all need to convert sugar to energy, is the root of the problem. The researchers concentrated on the nerves surrounding these cells, and told them to stop firing “emergency” messages to the nervous system. In the mice, this caused the islet cells to recover and begin functioning normally again. In other words, they were cured.

(Note: obviously the islet cells have to be inflamed, not dead, for this to work. That’s why I said at the beginning that you’d have to catch the disease within a certain period of time.)

Obviously if this holds true for humans as well, this is an incredibly huge development, not just for Type I, but for Type II diabetes as well:

They also discovered that their treatments curbed the insulin resistance that is the hallmark of Type 2 diabetes, and that insulin resistance is a major factor in Type 1 diabetes, suggesting the two illnesses are quite similar.

While this study concentrates solely on Diabetes Type I (or Juvenile Onset Diabetes), other diseases not previously linked to the nervous system may benefit from this research as well:

They also conclude … that nerves likely play a role in other chronic inflammatory conditions, such as asthma and Crohn’s disease.

This is potentially the biggest medical breakthrough since curing polio. Here’s hoping the research proves to be true and transferable to humans!

[tags]diabetes, medical breakthroughs, medical research, nervous system[/tags]

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